Wednesday, October 10, 2012

A perhaps idiosyncratic view.

So, as it turned out, I called this year's Nobel Prize for Chemistry.  While I am now curious if I have any Elven ancestry (Elrond had that gift of foresight, right?), I feel I should note the following for those feeling that biochemistry isn't really chemistry.

I like biological chemistry since, in my view, it allows me to explore so many areas of chemistry.  I've synthesized isotopically enriched small molecules, I've purified proteins, I've been able to work with multiple spectroscopic and physical measurement methods in detail, I've examined paramagnetic inorganic solids with both success and failure, I've spectroscopically dissected multicomponent organic solids, I've had to explore certain types of self-assembling systems, I've cranked through theoretical treatments of metalloenzyme catalysis as well as polymer chemistry to make sense of my data over the's been a good time.

Extending from that, I like chemistry since it is perfectly situated to go hopping over boundaries.  I don't see why I shouldn't be able to figure out signal transduction pathways just because I'm a chemist.  I don't see why I should humbly hand over fundamental questions about the theoretical basis for spectroscopic methods to the physicists.   

Although right now biochemistry is giving me a headache.  Speaking of which, back to it.....

P.S. - A hearty congratulations to both Serge Haroche & David Wineland as well as, of course, Robert Lefkowitz & Brian Kobilka!

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